At Kudrati Ayurved Health Center we provide highly results in Ayurvedic treatment of Sandhoff disease in Ahmedabad, Gujarat, India and around the world. Sandhoff disease is an autosomal recessive genetic disorder caused by an abnormal gene for the beta subunit of the hexosaminidase B (HEXB) enzyme. This gene abnormality results in a deficiency of enzymes called hexosaminidase A and B that are responsible for breaking down GM2 gangliosides made by the nerve cells.